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The successful functionalization of SBA-15 with thiol and amine groups provides a suitable platform for further conjugation with SNCDs and FA

As the most commonly used basic treatment for OSA patients, CPAP has been preliminarily shown to potentially improve the prognosis of OSA-associated lung cancer patients (Khalyfa et al., 2022

139 On the pathogenic side, hepatic accumulation of FFAs, oxidative stress, and gut barrier dysfunction lead to LPS translocation, activating the NLRP3 inflammasome

In some individuals, however, vaccination can also trigger inflammationpartly due to vaccine adjuvantsleading to the production of autoantibodies that target the thyroid gland (75, 89)

Those non-covalent compounds are highly specific and since they bind reversibly, they may exhibit a better safety profile ( in vivo activity (Zhuang et al., 2017), potentially because they are highly polar and hardly able to penetrate the BBB