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Combinatorial approaches addressing oxidative stress, neuroinflammation, and MG-induced damage may be promising

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The field shows growing interest in novel delivery systems, including liposomal formulations, sublingual preparations, and buccal absorption methods, attempting to overcome the documented challenges of glutathiones poor gastrointestinal bioavailability

Research has also shown that under serine-deficient conditions, pancreatic ductal adenocarcinoma (PDAC) cells maintain intracellular serine levels by upregulating PHGDH, adapting to the harsh microenvironment and promoting tumor progression (74)

Puerarin improves the bone micro-environment to inhibit OVX-induced osteoporosis via modulating SCFAs released by the gut microbiota and repairing intestinal mucosal integrity