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Description

Figure 2 Cellular Processes Linked to Redox Imbalance That Are Dysregulated in Als Protein Misfolding The presence of misfolded proteins is known to induce oxidative stress

Complex Intell

Gusarova GA, Trejo HE, Dada LA, Briva A, Welch LC, Hamanaka RB, Mutlu GM, Chandel NS, Prakriya M, Sznajder JI (2011) Hypoxia leads to Na, K-ATPase downregulation via Ca2+ release-activated Ca2+ channels and AMPK activation

And it disrupts sleep, which compounds everything else

[DOI] [PMC free article] [PubMed] [Google Scholar] 375.Martineau A.R., Jolliffe D.A., Hooper R.L., Greenberg L., Aloia J.F., Bergman P., Dubnov-Raz G., Esposito S., Ganmaa D., Ginde A.A., et al