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doi: 10.3389/fonc.2020.00429 290 A phase II Study of the Glutaminase Inhibitor Telaglenastat (CB-839) in Combination With the PARP Inhibitor Talazoparib in Participants With Metastatic Castration-Resistant Prostate Cancer (2021)

Antioxidants and endothelial nitric oxide synthesis

Considering the potential for therapeutic development of (in)GSH, the established safety and tolerability data, biological plausibility, and pilot level clinical evidence of benefit are further supported with this demonstration that (in)GSH is able to augment brain GSH levels

Proteins and membrane organelles controlled by mTOR complex 1 (mTORC1) upregulate autophagy [94, 95], causing the release of amino acids and lipids during prolonged nutritional deprivation

( E ) Oxygen consumption rate (OCR) values of matched GSC23 and DGC23 in Seahorse assays ( n = 10/group)

Helps maintain overall vitality and healthy aging support