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doi: 10.1186/1476-5918-8-1 [DOI] [PMC free article] [PubMed] [Google Scholar] [29].Reddy VP
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The compounds that were effective across multiple models were further tested as single agents and in combination with a clinically relevant protocol mimicking COJEC 12 , the five-chemotherapy cocktail (cisplatin, vincristine, carboplatin, etoposide and cyclophosphamide) that is the first line of action to treat HR-NB patients set by the International Society of Pediatric OncologyEuropean Neuroblastoma (SIOPEN) 6
[97] It is nontoxic, non-immunogenic, and has a net neutral charge that reduces non-specific protein-protein interactions
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Autophagy 16 (8), 14821505
