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The neurosteroids dehydroepiandrosterone sulfate and pregnenolone sulfate inhibit the UNC-49 GABA receptor through a common set of residues

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P7 was known with longstanding bowel problems with significant bloating, nausea, vomiting, and constipation and was found to have a slow gut motility

508 Nicorandil, an ATP-sensitive K + channel opener, alleviates cardiac microvascular injury by improving microvascular perfusion and structural integrity

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Beyond their digestive functions, BAs serve as critical signaling molecules regulating cholesterol homeostasis, energy metabolism, and nutrient assimilation
