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Description
As the transformed cells multiply, they outgrow the diffusion limits of oxygen, thus, becoming hypoxic

At best, it may serve as one piece of a larger, clinician-guided plan, but it should never be treated as a substitute for the fundamentals
T.ZieglerA

Colegrave, M.H
McBain, F.S

Statements Acknowledgments This work was supported by grants from University of PadovaMURST ex-60%. Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest
