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J Electroanal Chem Interfacial Electrochem 1986, 209:417428

UPLC-MS/MS and network pharmacology-based analysis of bioactive anti-depression compounds in betel nut

Furthermore, Fe 3 O 4 reacts with hydrogen peroxide, leading to a Fenton reaction, followed by the overproduction of hydroxyl radicals, which increases ROS levels and further induces ferroptosis in cells ( The second category of ferroptosis-related nanodrugs (for inhibiting intracellular GPX4 activity): In addition to promoting the intracellular Fenton reaction, these nanodrugs can inhibit GPX4 activity, thus reducing intracellular GSH levels

Interestingly, the actions mentioned above of GR may be modulated by other nuclear receptors specific for certain endocrine tumours, such as androgen receptors (ARs), estrogen receptors (ERs), or progesterone receptors (PRs)

Enzymatic or non-enzymatic, antioxidants are substances that prevent the formation of free radicals, and seek and neutralize or repair the damage caused by them ( ROS homeostasis is ensured by various antioxidant systems present both in plants (Sharma et al., 2012) and the human body (Poli et al., 2004