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Treatment options may include medications, physical therapy, injections, or surgery, depending on the underlying cause of the pain

Another case involved an anaphylactic shock after a hydroxocobalamin injection

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Some of these assessments are also done independently

No published research validates these dose-response relationships in humans

Persistent, severe nausea that does not improve within two weeks suggests the dose increase was too aggressive, and stepping back to the previous level for an additional four weeks is standard practice