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People who are vegetarians mainly rely on their endogenous production of carnitine.[ref] While the OCTN2 transporter is important in carnitine uptake, in some tissues, such as the lungs and intestines, carnitine can also be absorbed by passive diffusion.[ref][ref] The expression of the OCTN2 transporter is regulated by estrogen receptors and PPARs

doi:10.11909/j.issn.1671-5411.2015.04.014 Odai T, Terauchi M, Kato K, Hirose A, Miyasaka N

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Genetic factors also play a key role in the pathogenesis of psoriasis (204, 207)

The zwitterionic carnitine itself is transported by the almost ubiquitously expressed organic cation transporters OCTN1 and OCTN2 ( 7.4 values ranging from 6.80 to 1.64 (Supplementary Table S1), indicating the necessity for transporter-mediated cell membrane passage