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3,3 -diindolylmethane promotes bdnf and antioxidant enzyme formation via trkb/akt pathway activation for neuroprotection against oxidative stress-induced apoptosis in hippocampal neuronal cells

Therefore, understanding the mechanisms underlying the trafficking has biomedical significance as impaired BDNF trafficking has been implicated in a wide spectrum of neurodevelopmental, neuropsychiatric, and neurodegenerative conditions