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Specific effects documented in research include proliferation of hair follicle progenitor cells, extension of the anagen (growth) phase of the hair cycle, increased hair follicle size and density, formation of new dermal papilla structures, enhanced wound-induced hair neogenesis, and prevention of follicle miniaturization

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Regular injections are commonly used to brighten the skin , reduce pigmentation , and promote an even complexion

Pattern recognition receptor (PRR)-dependent pathway: cholesterol-rich microdomains exposed on the crystal surface directly bind to Toll-like receptors 2/4 (TLR2/4), thereby initiating the MyD88 signaling cascade (Narang and Dalbeth, 2020)

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