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Following chronic liver injury, HSCs proliferate, lose their vitamin A and undergo a major phenotypical transformation to -smooth muscle actin (-SMA) positive activated HSCs, which produce a wide variety of collagenous and non-collagenous extracellular matrix (ECM) proteins [168]
10.1021/acs.jpcb.6b02475 32 BarbarE.NyarkoA
It may just be more expensive
TCM-LAEC2023003)
Additionally, sleep disturbances can lead to altered activity of immune cells, including macrophages and natural killer cells
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