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Rights and permissions About this article Cite this article Dringen, R., Brandmann, M., Hohnholt, M.C

Bioinformatics analysis The putative biological relevance of the differentially expressed proteins was addressed through network analysis

Most studies focus on short-term use 2

GSH is negatively charged at physiological pH so it is unable to cross both the outer mitochondrial membrane (OMM) and the inner mitochondrial membrane (IMM)

This phenotype was explored in both mouse models and in vitro with an anti-IL-23 antibody to block IL-23 signaling where mice experienced prolonged survival and decreased tumor burden, and CD8 + cells in mice and in vitro showed enhanced cytotoxicity in the IL-23-depleted state [154] (Fig

Furthermore, the clinical success of abiraterone demonstrated that CRPC, which has previously been regarded as an androgen-independent disease, is still driven, at least in part, by androgens