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Our skin repairs itself, but this ability weakens over time

Supporting Skin Radiance from Within Daily lifestyle factors such as sun exposure, stress, lack of rest, environmental aggressors and ageing may affect the appearance of skin over time 1

Nature New Biology , 243(124), 8587

Regenerative processes in connective tissues

gallinarum in germ-free mice also recapitulated an LGS-like phenotype with enhanced bacterial translocation to the liver, presumably due to the induction of Hp/zonulin and the reciprocal downregulation of TJ-related molecules (e.g., Cldn3 and Ocln )