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In vivo studies demonstrated the effect of GSH on gene expression through chromatin remodeling [58]

Redox Signal 18 , 16231641 (2013)

A noninfectious synthetic peptide in a simple in vitro system may have a different risk profile from work involving primary human-derived cells, viral vectors, recombinant systems, infectious agents, animal tissues, or pathogen-bearing materials

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Now picture the same man, same drinks, same time frame but he spent the afternoon in the heat without drinking water and is mildly dehydrated