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doi:10.3389/fimmu.2019.02783 Hewison M

Further, the mutant atgsnor13 was also perturbed in thermotolerance and resistance to paraquat (1,1 -dimethyl-4,4 -bipyridinium dichloride), which induces the production of superoxide and H 2 O 2 in wild type leaves ( Arabidopsis GSNOR1/HOT5/PAR-2 gene not only regulates SA signaling and thermotolerance by modulating the intracellular SNO level, but also acts downstream of superoxide to regulate cell death

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Autophagy has been reported to be involved in rotenone-mediated neurotoxicity, based on LC3-II decreases 53