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Sci Transl Med 7(289):289ra84

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When someone takes benzodiazepines for an extended period, their body and brain become accustomed to the presence of the drug, and withdrawal can occur when they stop taking the drug

The peptide also attracts immune cells to wound sites, stimulates nerve growth, and promotes angiogenesis

However, a recent study conducted by DeNicola discovered that the glutamate-cysteine ligase catalytic subunit (GCLC) can defend against ferroptosis induced by cysteine deprivation through facilitating the formation of -glutamyl-peptides, which can be enhanced by NRF2 [66]

Our findings are in line with other reports showing a decrease in Sirt6 protein expression in transgenic mice (5XFAD) 133 as well as decreased gene and protein expression in AD patients 133,134