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Current Neuropharmacology, 16(5), 566-583

Chem Biol Interact 1998

doi: 10.1371/journal.pone.0067617 321 NimmerjahnAKirchhoffFHelmchenF
The K430R mutation markedly inhibited, while the K430Q mutation significantly enhanced the enzyme activity of PDH and -KGDH

Yet key controversies remain

I have been happily symptom free for years, and didnt even know my numbers were off until my most recent blood test
