homocysteine and glutathione peroxidase-1 Impaired Metabolism Atherothrombotic Disease Glutathione peroxidases as oncotargets |

Preclinical and clinical studies have demonstrated that bioactive compounds such as polyphenols, alkaloids, terpenoids, saponins, and flavonoids exert beneficial effects on AD-related pathways by reducing oxidative stress, suppressing neuroinflammation, preventing A aggregation, and modulating tau hyperphosphorylation (Liu et al., 2024)

Also, the protocol has been adopted by the Ethics of Animal Use in Research Committee of Zagazig University (ZU-IACUC), Egypt

386 Metabolic activities are orchestrated by a delicate interplay among cellular signaling pathways

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TABLE 1 Potential regulatory modes and regulators of ERS in SCI treatment