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YQ202305), Fundamental Research Funds for the Liaoning Province Doctoral Startup Project (Grant No

, Pfeiffer B., and Hamprecht B

Both targeted and non-targeted data analysis was applied

Figure 3 6.1 Based on epigenetic reprogramming Unlike classical adaptive immune memory, which relies on antigen receptor gene rearrangement, trained immunity operates through epigenetic modifications that increase chromatin accessibility at gene loci following primary stimulation

However, while these pathways are important, they are often disabled in cancers by mutations in master regulators such as TP53 and Bcl- 2, which allow for unbridled proliferation (Hemann and Lowe 2006)

This is fascinating. These stories need to be told