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Mitochondrial function was severely compromised on multiple levels, including abnormalities in mitochondrial biogenesis (PGC1), nutrient sensors regulating fatty-acid entry into mitochondria (pAMPK/AMPK, SirT3, CPT1b), mitochondrial -oxidation of fatty-acids (HADHA, PPAR), electron transport chain complexes (I, II, III, V), ATP synthesis (ATP5A), and mitophagy (PINK1)

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These approaches can uncover hidden patterns, prioritise key molecular features, and support predictive modelling across diverse omics layers (Reel et al

Conclusions In this review, the metabolism of thiol compounds was examined with a focus on the synthesis and degradation of cysteine, glutathione, and coenzyme A

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