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Expression of a dominant negative form of SREBP-1c blocked insulin-stimulated Gck expression in rat primary hepatocytes, whereas expression of an active form of SREBP-1c increased expression of Gck independently of insulin stimulation (94)

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In another series of experiments, the average bioavailability was of the peptide using nasal formulation 1 27.9% 9.7 and the mean bioavailability of the peptide using nasal formulation 2 34.7% 15.6, in both cases the bioavailability with the same amount of administered by intravenous injection Peptids was compared