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Description
It is commonly recommended for pets with conditions such as dilated cardiomyopathy (DCM) or congestive heart failure (CHF)

Rats were group-housed, three per cage, under controlled environmental conditions: a 12-h light/dark cycle (lights on at 7:30 AM and off at 7:30 PM), constant temperature (25 C), and ad libitum access to standard rodent chow (Rodent Diet CE-2, CLEA Japan, Tokyo, Japan) and tap water

Increase the dose beyond that point, and efficacy not only wanes, but it reverses

10.1371/journal.pone.0050568 54 ZhengJ.-L.LuoZ.LiuC.-X.ChenQ.-L.ZhuQ.-L.HuW.et al (2013)

Clin Ther 2003;25:13821406

Peltz, managing partner of Bartlit Beck
