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(R)-(+)--lipoic acid protected NG108-15 cells against H2O2-induced cell death through PI3K-Akt/GSK-3 pathway and suppression of NF--cytokines

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It is commonly accepted that oxidative stress induced by excess ROS/RNS levels is detrimental to biological functions and is involved in the development of many pathological conditions, such as cardiovascular diseases, neurodegenerative diseases, aging, and cancer (30, 90, 106)

APS attenuated the increase in cardiomyocyte surface area, improved cardiomyocyte viability, enhanced cardiac function, and reduced the heart weight-to-body weight (HW/BW) ratio in DCM rats

10.1196/annals.1297.059 [DOI] [PubMed] [Google Scholar] 46.Estrela JM, Ortega A, Obrador E

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