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[11] Long-term metformin therapy reduces calcium-dependent intrinsic-factor binding, lowering B12 absorption and potentially necessitating higher or more frequent parenteral doses

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It is especially useful where oral intake is insufficient or absorption is compromised, as noted in the product literature

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Handling & Storage: Store in a controlled, low-temperature environment Avoid repeated exposure to heat, moisture, and direct light Handle using appropriate laboratory safety procedures Compliance & Safety Disclaimer: This product is supplied in accordance with industry-standard research material practices