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Whatever the purpose, the regulatory and bioanalytical characteristics of the method should fit the needs of the program

Unbound and NAD + -bound TmRex are structurally very similar, while NADH binding induces significant structural changes

doi: 10.1101/cshperspect.a002584

Despite lower ATP production than OXPHOS does, this seemingly paradoxical metabolic phenotype provides advantages for rapidly proliferating malignant cells

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Van Der Velpen et al., 2019
