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As well as from poor diet and digestion, vitamin B12 deficiencies can also be affected by a genetic condition such as: o Pernicious anaemia o Crohns disease o Treatment with proton-pump inhibitors o Atrophic gastritis o Coeliac disease o Use of antacids (acid is required to release B12 from food) o Gastrointestinal surgery o Use of certain medications o Use of illegal drugs and substances including nitrous oxide

Broad clinical phenotypes associated with TAR-DNA binding protein (TARDBP) mutations in amyotrophic lateral sclerosis

doi: 10.7759/cureus.4985

In addition, RAS-selective lethal three induced-RPE ferroptosis shows the features of receptor-interacting protein kinase (RIPK)1/RIPK3 activation and lipid ROS accumulation (Tong et al., 2023)

Any references to skin, follicle, or extracellular-matrix pathways are provided only for research context and do not imply cosmetic or clinical use

Mitochondrial respiration as a target for neuroprotection and cognitive enhancement