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Description
Regulation of nucleolar signalling to p53 through NEDDylation of L11
On follow-up examination three months later, repeat dermoscopic imaging with polarized contact dermoscopy using ultrasound gel and a polyvinyl chloride barrier revealed significant changes concerning for melanoma, including increase in size, asymmetric darkening, and the appearance of structureless areas and central blue and pink colors (Figure 2b)
doi: 10.1093/neuros/nyz549
1 Rarer presentations include erosive nail lichen planus, yellow nail syndrome-like features, 4, 5 onychopapilloma, 6 and nail degloving
The black pigmentation extending to proximal nail fold was found to be the nail plate pigmentation visible through a translucent cuticle, known as pseudo- Hutchinsons sign [Figure 3]
About 90% were located in the interpalpebral area with relative equal distribution nasally and temporally (2)
