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In addition, both preclinical and clinical literature often underrepresent females, limiting insights into sex-specific immunometabolic and hormonal modulators of treatment response (Seyedinia et al., 2023

10.1007/s11427-017-9142-2 458 YuanB.LiaoF.ShiZ

Whether that stability translates to meaningful systemic circulation in humans is a question the published literature has not yet answered

J Alzheimers Dis 2011

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10.1083/jcb.202102146 82