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The procedure from example 9 is used, replacing 3-methoxyphenylacetylene with phenylacetylene and 2-methyl-6-iodobenzoic acid methyl ester with 2-methoxy-6-iodobenzoic acid methyl ester in the initial step 5-methyl-2-methoxy-cyclobenzaprine (from Example 9) is selectively 0-demethylated using boron tribromide

doi: 10.1039/d0cs00579g
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Avoid fake tans, facial waxing , chemical peels or laser treatments for up to one week prior to your treatment

Yes, noticeably so
