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Glutathione is required for essential body operations such as chemical and protein formation, tissue formation, and immune system support

doi: 10.1046/j.1464-5491.2001.00509.x

The NADPH needed for GRdependent GSSG reduction is regenerated in glucosefed cultured astrocytes mainly by the cytosolic pentosephosphate pathway (PPP) (Dringen et al

10.1093/oxfordjournals.aje.a010124 6 DobinA.DavisC

In addition, stimulation of neurosteroidogenesis by metyrapone was found to reduce cocaine intake in rats (Goeders and Guerin, 2008), and one could suppose a similar effect for alcohol intake

Minimal side effects include soreness at the injection site for a few hours to a few days