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If plateau persists despite dose escalation, your healthcare provider may recommend switching to tirzepatide (which acts on two receptor types rather than one) or adding a complementary agent through PlexusDx's GLP-Squared protocol

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Long story short: there isn't enough research into the subject for a definitive answer

Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial

Semaglutide, a GLP-1 receptor agonist, slows stomach emptying, increases feelings of fullness, and prompts the pancreas to release insulin only when blood sugar is elevated