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When glutamate was injected into the ganglia innervating the temporalis or masseter muscle, there was a significant increase in nociception (decrease in afferent mechanical thresholds) that was attenuated by NMDAR antagonists (2R)-amino-5-phosphonovaleric acid, AP-V) or worsened by EAAT blockers (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid, TFB- TBOA) [267]

Enhancing the HBP leads to increased UDP-GlcNAc and O-linked glycosylation, which impair eNOS activity [74]

This direct dissociation pathway is significant for methylcobalamin, and dominant for ethyl- and n-propylcobalamins

doi: 10.1292/jvms.18-0045

In: Wang, Z

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