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doi: 10.5603/EP.A2022.0030

10.7150/ijms.86533 27 MaW

While mutations of ETC proteins are rarely linked as a direct cause of PD (except for UQCRC1), impaired ETC proteins may not only lead to excessive ROS production, but also cause impeded mitophagy, -Syn aggregation, and apoptosis in PD pathogenesis

Conversely, SAM stimulates high K m hepatic methionine S-adenosyltransferase III and the alternative transmethylation pathway by activating glycine methyltransferase (Fig

Endocrinology 149 , 39093919 (2008)

References Appleyard CB and Wallace JL (1995)
