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For instance, transcriptomic analyses have shown that CAR-T cells from patients who achieved complete responses in CLL were enriched in a memory-associated gene signature, whereas CAR-T cells from non-responders exhibited gene expression patterns linked to effector differentiation
Piemonte, F
[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Kubo S.H., Rector T.S., Bank A.J
Hardie 2013
Nat Med 14(2):194
It cant be meaningfully patented because the structure is derived from an endogenous compound
