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Mechanisms of OR desensitization OR phosphorylation Numerous studies have been carried out to demonstrate the role of OR phosphorylation in desensitization by using chemical inhibitors of kinases, in vitro or in vivo knock-out (KO) of kinases using siRNA or transgenic mice, over-expression of dominant negative mutants of kinases, amino acid substitution or truncation on OR

The alpha7nACh-NMDA receptor complex is involved in cue-induced reinstatement of nicotine seeking

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They underwent TMS on the motor cortex using 30 pulses per 30 seconds at a frequency of 25 Hz for 10 days