dihexa human clinical trials safety D I H E X A is having a moment right now… and I get why. When something gets labeled as “brain repair” or “synapse growth,” it spreads FAST especially in communities Celebrating Clinical Trials Day -
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Stylianopoulos T, Poh MZ, Insin N, Bawendi MG, Fukumura D, Munn LL, Jain RK

### AOD-9604 Mechanism of Action AOD-9604 is believed to promote **fat loss** through: - Stimulation of lipolysis in adipose tissue via beta-3 adrenergic receptor pathways - Inhibition of lipogenesis (new fat formation) - No effect on growth hormone receptors (does not promote tissue growth) - No effect on IGF-1 levels or blood glucose Importantly, AOD-9604 does **not** suppress appetite or affect food intake it is purely a lipolytic **fat loss peptide**

So its inclusion is completely unnecessary for most and only has a minor health benefit or placebo effect
Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action

Moving from continuous dopaminergic stimulation to continuous drug delivery in the treatment of Parkinsons disease

349:5226 Hooper M