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Dendritic cells, as antigen-presenting cells, play a crucial role in activating T cells, leading to the differentiation of T helper 1 (Th1) and 17 (Th17) cells, which release inflammatory cytokines like interferon gamma (IFN-), TNF-, IL-17, and IL-22

The maximal activity of the dimeric macrocycles was observed at around 100 nM

Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinase gene

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