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Endogenous glutamate generated from glutamine via PAG may enter the TCA cycle via AAT (left side of neuron) while exogenous glutamate taken up from the extracellular space may be incorporated into the TCA cycle via GDH (right side of the neuron) FTD3 astrocytic glutamate uptake is upregulated whilst glutamate metabolism is largely maintained

The clinical trial was registered with the Chinese Clinical Trial Registry (registration number: ChiCTR2100049271) on July 28, 2021

Suitable for regular skincare routines, it supports brighter-looking skin and helps maintain a smoother, more even complexion with consistent use

doi: 10.1038/s41598-023-44142-2

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[20] showed that overexpression of GPX3 could inhibit the proliferation of PCa cells and the size of xenograft tumors in vivo