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It must undergo various transformations for utilization.) Folate is required for the following: Synthesis of nucleic acids (for DNA production and repair and tRNA Single carbon metabolism (methylation) Interconversion of amino acids (for neurotransmitter production and detoxification) Formation and maturation of RBC, WBC and platelet production

High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPTIA and CPTIC that regulate fatty acid metabolism

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