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10.1016/s0012-1606(03)00297-5 103 SuiL.BouwensL.MfopouJ
Research has demonstrated that celastrol induces paraptosis in breast cancer cells via the IP3R-dependent Ca 2+ signalling pathway, highlighting the critical role of Ca 2+ homeostasis disruption in this death pattern [124]
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while it helps sequester excess free iron, it may also act as a source of free iron during ferroptosis (Yang et al., 2022a)
