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Description
GPX4 protects cells from oxidative damage by lowering thymine hydroperoxides, cholesterol hydroperoxides, and fatty acid hydroperoxides in addition to utilizing GSH to remove harmful PL-OOH (30, 31)
Association between tamoxifen treatment and diabetes: a population-based study

Epub 2022/11/07

Inactivation of GPX4 in cells triggers the accumulation of lipid peroxides, leading to ferroptosis 28

Oral Patol
In addition to SIRT1 and SIRT2, SIRT3 is also a longevity factor and plays an important role in counteracting oxidative stress and preventing cellular senescence and tumorigenesis (Jing et al., 2011
