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Mitophagy, a form of autophagy, is responsible for the basal mitochondrial turnover that eliminates dysfunctional mitochondria

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Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]