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10.1038/180326a0 47 IngramV
Procopio-Melino et al optimized the cystine feeding scenario based on a formula factoring cell growth and protein contents, and eventually established a process resulting in a high expression titer and nearly fully TNB-capped antibody
Fracanzani AL, Burdick L, Raselli S, et al
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Acetoacetyl-CoA is then converted to 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA), followed by acetoacetate, and finally, -hydroxybutyrate (BHB) is supplied as a substrate for neuronal ATP synthesis
"It holds major theoretical and practical significance
