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More studies with larger sample sizes are needed in this area to make a general conclusion
Calcaterra V, Magenes VC, Massini G, De Sanctis L, Fabiano V, Zuccotti G
MTHFR is not only important for the formation of 5-MTHF (and thus the methionine cycle) but also for the regeneration of BH4
10.1007/s00018-016-2194-1 23 CardosoB
All relevant data are available within the cited publications
