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showed that despite treatment with NAC, in massive overdoses, patients with APAP concentrations above the 300 mcg/mL and 500 mcg/mL line on the Rumack-Matthew nomogram developed hepatotoxicity when compared with lower APAP concentrations

Levels of APP immunostaining provide a gold-standard for clinical identification of diffuse axonal injury both in brain and SCI (Blumbergs et al., 2014), which causes an accumulation of APP, other axonal transport proteins, intracellular components such as lysosomes, neurotrophin, mitochondria and synaptophysin-carrying vesicles

Beclin1 promotes autophagy and LC3 protein levels reflects autophagy induction (15)

10.1111/j.1749-6632.2000.tb05594.x 8 ChangB

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115 VargaL.SzigetiJ.KovcsR.FldesT.ButiS
