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Description
In this phase, the liver attaches a glutathione molecule to a toxin, making it water-soluble so the body can easily flush it out

Brains were subsequently embedded in the Optimal Cutting Temperature (OCT) compound and sectioned into 30-m-thick coronal prefrontal slices using a CM1860 Cryostat (Leica, Germany)

The yeast solids are removed by centrifuging or filtration

Results To investigate Chlamydia pneumoniae infection and its association with neuroinflammation and neurodegeneration in the AD retina, we analyzed retinal and brain tissues from a cohort of 104 patients: 51 with AD dementia (mean age SD: 85.90 10.06 years, 29 females/22 males), 16 with MCI due to AD (89.43 6.90 years, 7 females/9 males), and 37 normal cognition controls (83.96 10.96 years, 21 females/16 males)

In the last years, a link between gut microbiota composition and autoimmune diseases has been proven in murine models and hypothesized in humans owed to the interactions with both the innate and adaptive branches of immunity [179]

This underscores the need for further research to clarify the role of eosinophils in different physiological contexts
