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Safety signals, manufacturing issues, or regulatory requests for additional data could push the timeline back

John McDonnell, a pediatric immunologist, said he loves vitamin C because of its importance in a functioning immune system

The dominant model in immunometabolism emphasizes that as glycolytic effectors (Teff cells) become memory T cells, like naive T cells they reacquire quiescence and preferentially utilize fatty acid oxidation and oxidative phosphorylation, supported by their increased mitochondrial biomass (106)

Further, GSH is described to buffer endogenous electrophiles 77,78

Epigenetic state determines the in vivo efficacy of STING agonist therapy

This dynamic underscores the need for monitoring and stress-management strategies during both the early and prolonged phases of KD adherence
