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Safety signals, manufacturing issues, or regulatory requests for additional data could push the timeline back

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John McDonnell, a pediatric immunologist, said he loves vitamin C because of its importance in a functioning immune system

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The dominant model in immunometabolism emphasizes that as glycolytic effectors (Teff cells) become memory T cells, like naive T cells they reacquire quiescence and preferentially utilize fatty acid oxidation and oxidative phosphorylation, supported by their increased mitochondrial biomass (106)

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Further, GSH is described to buffer endogenous electrophiles 77,78

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Epigenetic state determines the in vivo efficacy of STING agonist therapy

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This dynamic underscores the need for monitoring and stress-management strategies during both the early and prolonged phases of KD adherence

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