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KIM-1 is a type I transmembrane protein molecule that is not detectable in healthy renal tissue, but is upregulated in de-differentiated proximal tubule epithelial cells after ischemic or toxic injury

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Meanwhile, 16 core targets were identified by PPI network analysis

[DOI] [Google Scholar] Yuan L

The mitochondrial version of fumarate hydratase (a 510 amino acid protein) is extended at the N-terminus, relative to the cytosolic form of the enzyme